Wiley Enzybiotics Antibiotic Enzymes As Drugs And Therapeutics January 2010 eBook

Wiley Enzybiotics Antibiotic Enzymes As Drugs And Therapeutics January 2010 eBook

Presents the latest research and applications for a new, promising approach
to fighting infectious diseases

Enzybiotics is a promising way of fighting bacterial or fungal infectious
diseases by using viruses or viral derived lysins. Drawing from the fields
of medicinal chemistry, microbiology, genetics, and biochemistry, this book
presents the state of the science in enzybiotics research, fully exploring
its emerging therapeutic applications.

The book begins with four chapters that review the potential applications,
possible advantages, and phylogeny of enzybiotics. Next, the book explores:

A new approach to controlling infections using Gram negative bacteria

Bacteriophage holins and their membrane disrupting activity

Anti staphylococcal lytic enzymes

Membrane targeted enzybiotics

Design of phage cocktails for therapy from a host range point of view

Novel methods to identify new enzybiotics

Genetically modified phages that deliver suicidal genes to target bacteria

The authors, all active enzybiotics researchers, offer a variety of
perspectives, the benefit of their own hands on investigations, as well as
a thorough review and analysis of the current literature.

As more and more bacteria become resistant to antibiotics, the development
of new disease fighting agents has become essential. This book demonstrates
the full potential of the emerging field of enzybiotics to control infectious
diseases. Moreover, it will serve as a springboard for new research and the
development of new therapeutics.

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